2010Biogerontology
Anisimov VN, Khavinson VKh
“Foundational rodent lifespan-extension work for short bioregulator peptides. SHR-mice cohort showed median-lifespan increases on chronic low-dose administration.”
↳ Topics · 3 papers · 1 editorial
Longevity & cellular aging.
The biological-vs-chronological-age question. Telomere maintenance, senescent-cell biology, and the small family of short peptides that show up in both literatures.
§ About this topic
Longevity research at the molecular level distinguishes biological from chronological age — measured through telomere length, epigenetic clocks, mitochondrial function, and senescent-cell load. A small group of short peptides has been studied across both major mechanism families: telomerase modulators (Khavinson's foundational rodent work, recent human cell-line measurements) and senolytic-adjacent peptides that influence the inflammatory secretome aging cells produce. Mostly preclinical, with a few human cell-line bridges.
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2025Biogerontology
Aldulaimi S et al
“Measures telomere length changes in human cell lines following short-peptide exposure, providing a translational anchor for the rodent literature.”
2026Front Aging
Mavrych V et al
“Surveys therapeutic peptide candidates studied in gerontology contexts, including telomerase modulators and senolytic-adjacent short peptides.”
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