Mechanism overviews · 29 papers
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↳ Research library · 9 peer-reviewed papers · 6 mechanism areas

Read the papers.

Every claim in the editorial body links back here. Each entry has the full Vancouver reference, the journal, the year, a one-paragraph plain-language paraphrase of what the paper actually shows, and a direct link to the source.

2024Cureus

Cushman DM, Holman A, Bouvette S, McCormick ZL

Narrative review of regenerative peptide signalling in soft-tissue and joint pathologies. Predominantly preclinical evidence base; human evidence is limited to case series.

2025Bone Joint J Open

Vasireddi N, Vasireddi N, Shah AK, et al

Reviews orthopaedic-context peptide signalling: VEGF, fibroblast collagen deposition, and inflammatory phase modulation in tendon and ligament repair models.

2010Biogerontology

Anisimov VN, Khavinson VKh

Foundational rodent lifespan-extension work for short bioregulator peptides. SHR-mice cohort showed median-lifespan increases on chronic low-dose administration.

2025Biogerontology

Aldulaimi S et al

Measures telomere length changes in human cell lines following short-peptide exposure, providing a translational anchor for the rodent literature.

2026Front Aging

Mavrych V et al

Surveys therapeutic peptide candidates studied in gerontology contexts, including telomerase modulators and senolytic-adjacent short peptides.

2025Endocrinol Metab Clin

Yoon J et al

Cross-sectional study of mitochondrial-derived peptide levels against metabolic biomarkers. Correlative; not causal.

2023Cell Metab

Zheng Y et al

Reviews evidence for mitochondrial-derived peptides as exercise-mimetic candidates. Mixed signals across studies; no consensus on outcome equivalence.

2020Cosmetics

Dou Y et al

Topical-route review of copper-peptide complex effects on collagen, elastin, and barrier proteins in dermal models.

2026Nutrients

Gong T et al

RCT measuring slow-wave activity and sleep onset following walnut-derived peptide administration in adults with mild sleep complaints.

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